NMR sample preparation guidelines
Protein sample concentration In NMR spectroscopy, the signal intensity is directly dependent on the concentration of the sample, with higher
Accelerating drug discovery and development with advanced NMR Solutions – From hit to lead
Driving breakthroughs in drug discovery and development industry.
At NMR-Bio, we empower pharmaceutical and biotech companies to accelerate drug discovery and development through cutting-edge NMR technologies. From hit identification to lead optimization, our high-resolution solutions provide precise characterization of small molecules and biologics, ensuring safer, more effective therapeutic approaches.
In the complex context of drug discovery, where vast amounts of data are generated and analyzed, our expertise supports research across different stages from early drug-repositioning efforts to the development of non-toxic, effective treatments.
We address challenges such as drug-protein interactions, optimizing research processes to deliver patients faster to clinical trials. As the pharmaceutical industry embraces innovation, NMR-Bio remains at the forefront of interpretable data analysis, enhancing drug discovery research with techniques that support thorough literature review, reliable data interpretation, and precise insights. Whether you’re working with big data, developing novel compounds, or tackling opportunities and challenges in drug design, we provide tailored solutions that ensure the highest standards of accuracy and efficiency.
Our expertise in drug discovery and development: advanced NMR solutions to overcome industry challenges.
At NMR-Bio, our expertise spans a wide range of areas in drug discovery and development. From drug repositioning to the discovery of new therapeutic approaches, we provide comprehensive support that ensures your research progresses seamlessly through the drug-discovery process.
Whether you are working with molecular interactions, optimizing drug candidates, or tackling complex drug-protein interactions, our tailored solutions address every stage of your research journey – from hit identification to lead optimization and beyond.
By leveraging our advanced technologies and scientific expertise, we help you overcome challenges and unlock new opportunities to accelerate your progress.
Custom protein production and isotopic labeling services
NMR-Bio provides advanced labeling protocols across various expression systems, including E. coli, cell-free systems, insect, and mammalian cells. Our expertise in producing high-quality, reproducible proteins supports critical stages of drug discovery, including drug design, drug repurposing, and the development of novel compounds. We excel in producing methyl-labeled monoclonal antibodies in CHO cells, delivering robust data essential for accurate analysis in contexts ranging from structural studies to vaccine development.
Protein NMR Spectroscopy Services
Our cutting-edge NMR technology accelerates integrated drug discovery, from hit identification to lead optimization. Our facilities provide the highest standards of accuracy and reliability. We support pharmaceutical companies in overcoming challenges associated with drug-protein interactions, optimizing drug safety, and ensuring precision in the discovery of novel therapeutic molecules. We can provide detailed 3D structures of proteins and peptides and analyze ligand-protein interactions, structural stability, and folding at atomic resolution.
Biophysical characterization
Comprehensive biophysical characterization is essential for understanding protein structure, stability, interactions, and dynamics as well as extracting kinetic and thermodynamic data. Our services include analysis of complex drug discovery research contexts, such as oncology, COVID-19, and other critical therapeutic areas. We provide rapid, precise insights into the development process, supporting your efforts in rethinking drug discovery to accelerate patients’ access to new medicines. Our expertise helps optimize data from systematic reviews, comprehensive reviews, and large volumes of scientific literature.
Isotopically labeled amino acids and proteins
NMR-Bio offers a wide range of user-friendly kits for methyl-specific labeling of large recombinant proteins expressed in E. coli. We also provide methyl isotopically labeled amino acids for recombinant protein expression in both cell-free and eukaryotic systems. Our catalog features high-quality isotopically labeled proteins optimized for NMR and mass spectrometry (MS) applications, enabling precise data acquisition for studies involving drug discovery research, therapeutic molecules, and precision medicine.
More than just an NMR provider, NMR-Bio is your strategic partner throughout your scientific journey.
Through tailored biopharmaceutical solutions and a collaborative approach, we help you make data-driven decisions that accelerate the development of novel drugs and advance your research toward clinical trials.
What speaks best about us? Our clients.
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NMR of large proteins: mastering methyl labeling for high-resolution analysis
The advent of selective methyl labeling for the study of proteins by NMR NMR-Bio manufactures and distributes high-quality amino acids
Get in touch to accelerate your drug discovery process.
Partner with NMR-Bio to drive your drug discovery and development forward. Whether you’re optimizing drug candidates, discovering new molecules, or tackling complex drug-protein interactions, we provide tailored solutions to meet your research needs.
From drug repositioning to the discovery of novel therapeutic approaches, our expertise helps you overcome challenges and unlock new opportunities. Let’s discuss how we can support your scientific goals and accelerate your progress.